What This Document Is
This is a lab assignment for BIOL 322 Genetics Lab at Western Washington University, focused on exploring the connection between genes, genetic databases, and human disease – specifically cancer. The assignment centers around investigating specific genes and utilizing online resources like OMIM and ENTREZ to understand their function and evolutionary relationships. It requires students to analyze gene information and synthesize findings into a comprehensive report.
Why This Document Matters
This assignment is crucial for students in a genetics lab course seeking to develop practical skills in bioinformatics and genomic research. It’s particularly valuable for those preparing for further study in genetics, molecular biology, or related health sciences. Students will benefit from completing this assignment when they need to learn how to navigate complex biological databases, interpret gene information, and connect molecular mechanisms to human phenotypes. It reinforces understanding of core concepts like gene function, mutation analysis, and homology.
Common Limitations or Challenges
This assignment requires independent research and critical thinking. It does *not* provide step-by-step instructions or pre-filled answers. Students will need to actively engage with online databases and interpret scientific information. The assignment also assumes a foundational understanding of genetics concepts like DNA replication, protein function, and mutation repair mechanisms. It doesn’t include a detailed review of these foundational topics.
What This Document Provides
* A list of genes associated with various cancers (e.g., Leukemia, Lymphoma, Colon Cancer) to investigate.
* Guidance on utilizing online resources like OMIM (Online Mendelian Inheritance in Man) and ENTREZ for gene analysis.
* A series of analytical questions requiring students to translate gene acronyms, determine chromosomal locations, and explain gene function.
* Instructions for submitting a “work-up file” containing detailed answers and supporting screenshots.
* Specific requirements for note-taking and image capture for lab documentation.
* A link to supplemental lecture material on cancer genetics.
